A tutorial on statistical methods for population association studies

Author:

Balding David J.

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Genetics,Molecular Biology

Reference109 articles.

1. Jobling, M. A., Hurles, M. E. & Tyler-Smith, C. Human Evolutionary Genetics: Origins Peoples & Disease (Garland Science, New York, 2004).

2. Thomas, D. C. Statistical Methods in Genetic Epidemiology (Oxford Univ. Press, 2004). The best general reference for statistical methods in genetic epidemiology; for population association studies it discusses important general issues without specific details on tests and other analyses.

3. Nielsen, D. M., Ehm, M. G. & Weir, B. S. Detecting marker–disease association by testing for Hardy–Weinberg disequilibrium at a marker locus. Am. J. Hum. Genet. 63, 1531–1540 (1998).

4. Wittke-Thompson, J. K., Pluzhnikov, A. & Cox, N. J. Rational inferences about departures from Hardy–Weinberg equilibrium. Am. J. Hum. Genet. 76, 967–986 (2005).

5. Conrad, D. F., Andrews, T. D., Carter, N. P., Hurles, M. E. & Pritchard, J. K. A high-resolution survey of deletion polymorphism in the human genome. Nature Genet. 38, 75–81 (2006).

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