P42 Ebp1 regulates the proteasomal degradation of the p85 regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70/CHIP-Reference-Cited by-同舟云学术

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P42 Ebp1 regulates the proteasomal degradation of the p85 regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70/CHIP

Published:2014-03 Issue:3 Volume:5 Page:e1131-e1131
ISSN:2041-4889
Container-title:Cell Death & Disease
language:en
Short-container-title:Cell Death Dis

Author:

Ko H R,Kim C K,Lee S B,Song J,Lee K-H,Kim K K,Park K W,Cho S-W,Ahn J-Y

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Link

http://www.nature.com/articles/cddis201479.pdf

Reference45 articles.

1. Ahn JY, Liu X, Liu Z, Pereira L, Cheng D, Peng J et al. Nuclear Akt associates with PKC-phosphorylated Ebp1, preventing DNA fragmentation by inhibition of caspase-activated DNase. EMBO J 2006; 25: 2083–2095.

2. Liu Z, Ahn JY, Liu X, Ye K . Ebp1 isoforms distinctively regulate cell survival and differentiation. Proc Natl Acad Sci USA 2006; 103: 10917–10922.

3. Liu Z, Oh SM, Okada M, Liu X, Cheng D, Peng J et al. Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor. Mol Biol Cell 2009; 20: 757–768.

4. Monie TP, Perrin AJ, Birtley JR, Sweeney TR, Karakasiliotis I, Chaudhry Y et al. Structural insights into the transcriptional and translational roles of Ebp1. EMBO J 2007; 26: 3936–3944.

5. Zhang Y, Hamburger AW . Heregulin regulates the ability of the ErbB3-binding protein Ebp1 to bind E2F promoter elements and repress E2F-mediated transcription. J Biol Chem 2004; 279: 26126–26133.

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1. Unveiling the role of PIK3R1 in cancer: A comprehensive review of regulatory signaling and therapeutic implications;Seminars in Cancer Biology;2024-11

2. EBP1 promotes the malignant biological behaviors of kidney renal clear cell carcinoma through activation of p38/HIF-1α signaling pathway;Cancer Cell International;2024-07-24

3. The structure and function of multifunctional protein ErbB3 binding protein 1 (Ebp1) and its role in diseases;Cell Biology International;2024-06-17

4. Von Hippel Lindau tumor suppressor controls m6A-dependent gene expression in renal tumorigenesis;Journal of Clinical Investigation;2024-04-15

5. CHIP promotes CAD ubiquitination and degradation to suppress the proliferation and colony formation of glioblastoma cells;Cellular Oncology;2023-11-20

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