CD99 ligation upregulates HSP70 on acute lymphoblastic leukemia cells and concomitantly increases NK cytotoxicity

Author:

Husak Z,Dworzak M N

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

Reference33 articles.

1. Kovar H, Dworzak M, Strehl S, Schnell E, Ambros IM, Ambros PF et al. Overexpression of the pseudoautosomal gene MIC2 in Ewing sarcoma and peripheral primitive neuroectodermal tumor. Oncogene 1990; 5: 1067–1070.

2. Dworzak MN, Fritsch G, Buchinger P, Fleischer C, Printz D, Zellner A et al. Flow cytometric assessment of human MIC 2 expression in bone marrow, thymus, and peripheral blood. Blood 1994; 83: 415–425.

3. Dworzak MN, Fritsch G, Fleischer C, Printz D, Fröschl G, Buchinger P et al. CD99 (MIC2) expression in paediatric B-lineage leukaemia/lymphoma reflects maturation-associated patterns of normal B-lymphopoiesis. Br J Haemat 1999; 105: 690–695.

4. Husak Z, Printz D, Schumich A, Pötschger U, Dworzak MN . Death induction by CD99 ligation in TEL/AML1-positive acute lymphoblastic leukemia and normal B-cell precursors. J Leuk Biol 2010; 88: 405–412.

5. Hahn JH, Kim MK, Choi EY, Kim SH, Sohn HW, Ham DI et al. CD99 (MIC2) regulates the LFA-1/ICAM-1-mediated adhesion of lymphocytes, and its gene encodes both positive and negative regulators of cellular adhesion. J Immunol 1997; 159: 2250–2258.

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