Hypoglycaemic and insulinotropic effects of a novel oral antidiabetic agent, (−)-N-(trans-4-isopropylcyclohexane-carbonyl)-d-phenylalanine (A-4166)

Author:

Ikenoue Takao,Akiyoshi Megumi,Fujitani Shoji,Okazaki Kyoko,Kondo Nobuo,Maki Toshio

Publisher

Wiley

Subject

Pharmacology

Reference38 articles.

1. Akiyoshi , M. Fujitani , S. Ikenoue , T. Okazaki , K. Kondo , N. Maki , T. Kikuchi , M. 1994 Possible therapy for postprandial hyperglycemia with strict glycemic control by a newly developed hypoglycemic agent, A-4166 15 th International Diabetes Federation Congress (Abstract) 419

2. A newly hypoglycemic agent, A-4166, inhibits Atp-sensitive potassium channels in rat pancreatic β-cells;Akiyoshi;Am. J. Physiol.,1995

3. Glibenclamide-associated hypoglycaemia: a report on 57 cases;Asplund;Diabetologia,1983

4. Mechanism of action of sulphonylureas with special reference to the extrapancreatic effect: An overview;Beck-Nielsen;Diabetic Med,1988

5. Relationship between the inhibition constant (Kd) and the concentration of inhibitor which causes 50 percent inhibition (I50) of an enzymatic reaction;Cheng;Biochem. Pharmacol.,1973

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