An autophagy-inducing and TLR-2 activating BCG vaccine induces a robust protection against tuberculosis in mice-Reference-Cited by-同舟云学术

An autophagy-inducing and TLR-2 activating BCG vaccine induces a robust protection against tuberculosis in mice

Published:2019-08-05 Issue:1 Volume:4 Page:
ISSN:2059-0105
Container-title:npj Vaccines
language:en
Short-container-title:npj Vaccines

Author:

Khan Arshad^ORCID,Bakhru Pearl,Saikolappan Sankaralingam,Das Kishore,Soudani Emily,Singh Christopher R.,Estrella Jaymie L.,Zhang Dekai,Pasare Chandrashekhar^ORCID,Ma Yue,Sun Jianjun,Wang Jin,Hunter Robert L.,Tony Eissa N.,Dhandayuthapani Subramanian,Jagannath Chinnaswamy

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Infectious Diseases,Pharmacology,Immunology

Link

http://www.nature.com/articles/s41541-019-0122-8.pdf

Reference128 articles.

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2. Rook, G. A., Hernandez-Pando, R., Dheda, K. & Teng Seah, G. IL-4 in tuberculosis: implications for vaccine design. Trends Immunol. 25, 483–488 (2004).

3. Armitige, L. Y., Jagannath, C., Wanger, A. R. & Norris, S. J. Disruption of the genes encoding antigen 85A and antigen 85B of Mycobacterium tuberculosis H37Rv: effect on growth in culture and in macrophages. Infect. Immun. 68, 767–778 (2000).

4. Katti, M. K. et al. The Delta fbpA mutant derived from Mycobacterium tuberculosis H37Rv has an enhanced susceptibility to intracellular antimicrobial oxidative mechanisms, undergoes limited phagosome maturation and activates macrophages and dendritic cells. Cell Microbiol. 10, 1286–1303 (2008).

5. Saikolappan, S. et al. The fbpA/sapM double knock out strain of Mycobacterium tuberculosis is highly attenuated and immunogenic in macrophages. PLoS ONE 7, e36198 (2011).

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