COVID-19 and influenza vaccine uptake among pregnant women in national cohorts of England and Wales

Author:

Gu XinchunORCID,Agrawal Utkarsh,Midgley William,Bedston StuartORCID,Anand Sneha N.,Goudie Rosalind,Byford Rachel,Joy Mark,Jamie GavinORCID,Hoang Uy,Ordóñez-Mena Jose M.,Robertson ChrisORCID,Hobbs F. D. Richard,Akbari AshleyORCID,Sheikh AzizORCID,de Lusignan SimonORCID

Abstract

AbstractVaccines against COVID-19 and influenza can reduce the adverse outcomes caused by infections during pregnancy, but vaccine uptake among pregnant women has been suboptimal. We examined the COVID-19 and influenza vaccine uptake and disparities in pregnant women during the COVID-19 pandemic to inform vaccination interventions. We used data from the Oxford-Royal College of General Practitioners Research and Surveillance Centre database in England and the Secure Anonymised Information Linkage Databank in Wales. The uptake of at least one dose of vaccine was 40.2% for COVID-19 and 41.8% for influenza among eligible pregnant women. We observed disparities in COVID-19 and influenza vaccine uptake, with socioeconomically deprived and ethnic minority groups showing lower vaccination rates. The suboptimal uptake of COVID-19 and influenza vaccines, especially in those from socioeconomically deprived backgrounds and Black, mixed or other ethnic groups, underscores the necessity for interventions to reduce vaccine hesitancy and enhance acceptance in pregnant women.

Funder

UK Research and Innovation (grant ref MC_PC_20058) Health Data Research UK

Publisher

Springer Science and Business Media LLC

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