Retention of heroin and morphine–6β–glucuronide analgesia in a new line of mice lacking exon 1 of MOR–1

Author:

Schuller Alwin G.P.,King Michael A.,Zhang Jiwen,Bolan Elizabeth,Pan Ying–Xian,Morgan Daniel J.,Chang Albert,Czick Maureen E.,Unterwald Ellen M.,Pasternak Gavril W.,Pintar John E.

Publisher

Springer Science and Business Media LLC

Subject

General Neuroscience

Reference30 articles.

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2. Way, E. L., Young, J. & Kemp, J. Metabolism of heroin and its pharmacological implications. Bull. Narcotics 17, 25–33 (1965).

3. Way, E., Kemp, J., Young, J. & Grasetti, D. R. The pharmacologic effects of heroin in relationship to its rate of biotransformation. Pharmacol. Exp. Ther. 129, 144–154 (1960).

4. Oldendorf, W. H., Hyman, S., Braun, L. & Oldendorf, S. Z. Blood–brain barrier: penetration of morphine, codeine, heroin, and methadone after carotid injection. Science 178, 984–986 (1972).

5. Inturrisi, C. E. et al. The pharmacokinetics of heroin in patients with chronic pain. N. Engl. J. Med. 310, 1213–1217 (1984).

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