Biosynthesis and biotechnological production of the anti-obesity agent celastrol-Reference-Cited by-同舟云学术

Biosynthesis and biotechnological production of the anti-obesity agent celastrol

Published:2023-06-26 Issue:9 Volume:15 Page:1236-1246
ISSN:1755-4330
Container-title:Nature Chemistry
language:en
Short-container-title:Nat. Chem.

Author:

Zhao Yong^ORCID,Hansen Nikolaj L.,Duan Yao-Tao^ORCID,Prasad Meera,Motawia Mohammed S.^ORCID,Møller Birger L.^ORCID,Pateraki Irini^ORCID,Staerk Dan^ORCID,Bak Søren^ORCID,Miettinen Karel^ORCID,Kampranis Sotirios C.^ORCID

Funder

Novo Nordisk Fonden

Publisher

Springer Science and Business Media LLC

Subject

General Chemical Engineering,General Chemistry

Link

https://www.nature.com/articles/s41557-023-01245-7.pdf

Reference59 articles.

1. Olshansky, S. J. et al. A potential decline in life expectancy in the United States in the 21st century. N. Engl. J. Med. 352, 1138–1145 (2005).

2. Liu, J., Lee, J., Salazar Hernandez, M. A., Mazitschek, R. & Ozcan, U. Treatment of obesity with celastrol. Cell 161, 999–1011 (2015).

3. Ma, X. et al. Celastrol protects against obesity and metabolic dysfunction through activation of a HSF1-PGC1α transcriptional axis. Cell Metab. 22, 695–708 (2015).

4. Hu, M. et al. Celastrol-induced Nur77 interaction with TRAF2 alleviates inflammation by promoting mitochondrial ubiquitination and autophagy. Mol. Cell 66, 141–153.e6 (2017).

5. Peng, S. Z. et al. Phase separation of Nur77 mediates celastrol-induced mitophagy by promoting the liquidity of p62/SQSTM1 condensates. Nat. Commun. 12, 5989 (2021).

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Celastrol: A century-long journey from the isolation to the biotechnological production and the development of an antiobesity drug;Current Opinion in Plant Biology;2024-10

2. Chemical tools for unpicking plant specialised metabolic pathways;Current Opinion in Plant Biology;2024-08

3. Plant drugs: Transcending the mescaline biosynthesis;Current Biology;2024-08

4. Intein-mediated temperature control for complete biosynthesis of sanguinarine and its halogenated derivatives in yeast;Nature Communications;2024-06-19

5. Reconstitution and optimization of complex plant natural product biosynthetic pathways in microbial expression systems;Current Opinion in Biotechnology;2024-06