A glycan gate controls opening of the SARS-CoV-2 spike protein-Reference-Cited by-同舟云学术

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A glycan gate controls opening of the SARS-CoV-2 spike protein

Published:2021-08-19 Issue:10 Volume:13 Page:963-968
ISSN:1755-4330
Container-title:Nature Chemistry
language:en
Short-container-title:Nat. Chem.

Author:

Sztain Terra,Ahn Surl-Hee^ORCID,Bogetti Anthony T.,Casalino Lorenzo^ORCID,Goldsmith Jory A.,Seitz Evan^ORCID,McCool Ryan S.,Kearns Fiona L.,Acosta-Reyes Francisco,Maji Suvrajit^ORCID,Mashayekhi Ghoncheh,McCammon J. Andrew^ORCID,Ourmazd Abbas^ORCID,Frank Joachim,McLellan Jason S.,Chong Lillian T.^ORCID,Amaro Rommie E.^ORCID

Funder

National Science Foundation

U.S. Department of Health & Human Services | NIH | Office of Extramural Research, National Institutes of Health

U.S. Department of Health & Human Services | National Institutes of Health

Publisher

Springer Science and Business Media LLC

Subject

General Chemical Engineering,General Chemistry

Link

https://www.nature.com/articles/s41557-021-00758-3.pdf

Reference30 articles.

1. Chan, J. F.-W. et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet 395, 514–523 (2020).

2. Lu, R. et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 395, 565–574 (2020).

3. Li, F. Structure, function, and evolution of coronavirus spike proteins. Annu. Rev. Virol. 3, 237–261 (2016).

4. Wrapp, D. et al. Cryo-EM structure of the 2019-NCoV spike in the prefusion conformation. Science 367, 1260–1263 (2020).

5. Walls, A. C. et al. Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein. Cell 181, 281–292.e6 (2020).

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