Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Chemical Engineering,General Chemistry
Link
http://www.nature.com/articles/s41557-018-0033-8.pdf
Reference59 articles.
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3. Dandapani, S. & Marcaurelle, L. A. Grand Challenge commentary: accessing new chemical space for ‘undruggable’ targets. Nat. Chem. Biol. 6, 861–863 (2010).
4. Brenner, S. & Lerner, R. A. Encoded combinatorial chemistry. Proc. Natl Acad. Sci. USA 89, 5381–5383 (1992).
5. Gartner, Z. J. & Liu, D. R. The generality of DNA-templated synthesis as a basis for evolving non-natural small molecules. J. Am. Chem. Soc. 123, 6961–6963 (2001).
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