Expanding the antibacterial selectivity of polyether ionophore antibiotics through diversity-focused semisynthesis
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Chemical Engineering,General Chemistry
Link
http://www.nature.com/articles/s41557-020-00601-1.pdf
Reference56 articles.
1. Huffman, B. J. & Shenvi, R. A. Natural products in the ‘marketplace’: interfacing synthesis and biology. J. Am. Chem. Soc. 141, 3332–3346 (2019).
2. Schreiber, S. L. Target-oriented and diversity-oriented organic synthesis in drug discovery. Science 287, 1964–1969 (2000).
3. Wetzel, S., Bon, R. S., Kumar, K. & Waldmann, H. Biology-oriented synthesis. Angew. Chem. Int. Ed. 50, 10800–10826 (2011).
4. Könst, Z. A. et al. Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides. Nat. Chem. 9, 1140–1149 (2017).
5. Wilson, R. M. & Danishefsky, S. J. Small molecule natural products in the discovery of therapeutic agents: the synthesis connection. J. Org. Chem. 71, 8329–8351 (2006).
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