Protein-templated ligand discovery via the selection of DNA-encoded dynamic libraries
Author:
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41557-024-01442-y.pdf
Reference138 articles.
1. Brenner, S. & Lerner, R. A. Encoded combinatorial chemistry. Proc. Natl Acad. Sci. USA 89, 5381–5383 (1992).
2. Needels, M. C. et al. Generation and screening of an oligonucleotide-encoded synthetic peptide library. Proc. Natl Acad. Sci. USA 90, 10700–10704 (1993).
3. Huang, Y., Li, Y. & Li, X. Strategies for developing DNA-encoded libraries beyond binding assays. Nat. Chem. 14, 129–140 (2022).
4. Satz, A. L., Kuai, L. & Peng, X. Selections and screenings of DNA-encoded chemical libraries against enzyme and cellular targets. Bioorg. Med. Chem. Lett. 39, 127851 (2021).
5. Kodadek, T., Paciaroni, N. G., Balzarini, M. & Dickson, P. Beyond protein binding: recent advances in screening DNA-encoded libraries. Chem. Commun. 55, 13330–13341 (2019).
Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Light‐Induced Unlocking Reactivity of Fragments for Fast Target‐Guided Synthesis of Carbonic Anhydrase Inhibitors;Angewandte Chemie;2024-09-05
2. Light‐Induced Unlocking Reactivity of Fragments for Fast Target‐Guided Synthesis of Carbonic Anhydrase Inhibitors;Angewandte Chemie International Edition;2024-09-05
3. Using DNA-encoded libraries of fragments for hit discovery of challenging therapeutic targets;Expert Opinion on Drug Discovery;2024-05-16
4. Isothiocyanate intermediates facilitate divergent synthesis of N-heterocycles for DNA-encoded libraries;Chemical Communications;2024
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3