Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes

Author:

Webber J P,Spary L K,Sanders A J,Chowdhury R,Jiang W G,Steadman R,Wymant J,Jones A T,Kynaston H,Mason M D,Tabi Z,Clayton A

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Reference43 articles.

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2. Kojima Y, Acar A, Eaton EN, Mellody KT, Scheel C, Ben-Porath I et al. Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts. Proc Natl Acad Sci 2010; 107: 20009–20014.

3. Olumi AF, Grossfeld GD, Hayward SW, Carroll PR, Tlsty TD, Cunha GR . Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res 1999; 59: 5002–5011.

4. Tuxhorn JA, McAlhany SJ, Yang F, Dang TD, Rowley DR . Inhibition of transforming growth factor-β activity decreases angiogenesis in a human prostate cancer-reactive stroma xenograft model. Cancer Res 2002; 62: 6021–6025.

5. Tuxhorn JA, Ayala GE, Smith MJ, Smith VC, Dang TD, Rowley DR . Reactive stroma in human prostate cancer. Clin Cancer Res 2002; 8: 2912–2923.

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