mTORC1-mediated translational elongation limits intestinal tumour initiation and growth-Reference-Cited by-同舟云学术

mTORC1-mediated translational elongation limits intestinal tumour initiation and growth

Published:2014-11-05 Issue:7535 Volume:517 Page:497-500
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Faller William J.,Jackson Thomas J.,Knight John R. P.,Ridgway Rachel A.,Jamieson Thomas,Karim Saadia A.,Jones Carolyn,Radulescu Sorina,Huels David J.,Myant Kevin B.,Dudek Kate M.,Casey Helen A.,Scopelliti Alessandro,Cordero Julia B.,Vidal Marcos,Pende Mario,Ryazanov Alexey G.,Sonenberg Nahum,Meyuhas Oded,Hall Michael N.,Bushell Martin,Willis Anne E.,Sansom Owen J.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature13896.pdf

Reference44 articles.

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3. Ashton, G. H. et al. Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling. Dev. Cell 19, 259–269 (2010)

4. Fujishita, T., Aoki, K., Lane, H. A., Aoki, M. & Taketo, M. M. Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcΔ716 mice. Proc. Natl Acad. Sci. USA 105, 13544–13549 (2008)

5. Gulhati, P. et al. Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer. Clin. Cancer Res. 15, 7207–7216 (2009)

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