Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis-Reference-Cited by-同舟云学术

Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

Published:2014-06-29 Issue:7512 Volume:512 Page:69-73
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Vande Walle Lieselotte,Van Opdenbosch Nina,Jacques Peggy,Fossoul Amelie,Verheugen Eveline,Vogel Peter,Beyaert Rudi,Elewaut Dirk,Kanneganti Thirumala-Devi,van Loo Geert,Lamkanfi Mohamed

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/nature13322.pdf

Reference26 articles.

1. Burger, D., Dayer, J. M., Palmer, G. & Gabay, C. Is IL-1 a good therapeutic target in the treatment of arthritis? Best Pract. Res. Clin. Rheumatol. 20, 879–896 (2006)

2. Matmati, M. et al. A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis. Nature Genet. 43, 908–912 (2011)

3. Lamkanfi, M. & Dixit, V. M. Inflammasomes and their roles in health and disease. Annu. Rev. Cell Dev. Biol. 28, 137–161 (2012)

4. Bauernfeind, F. G. et al. Cutting edge: NF-κB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J. Immunol. 183, 787–791 (2009)

5. Wertz, I. E. et al. De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling. Nature 430, 694–699 (2004)

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