Lipid-accumulated reactive astrocytes promote disease progression in epilepsy
Author:
Funder
National Natural Science Foundation of China
Postdoctoral Research Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
General Neuroscience
Link
https://www.nature.com/articles/s41593-023-01288-6.pdf
Reference62 articles.
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2. Löscher, W., Potschka, H., Sisodiya, S. M., Vezzani, A. & Barker, E. L. Drug resistance in epilepsy: clinical impact, potential mechanisms, and new innovative treatment options. Pharmacol. Rev. 72, 606–638 (2020).
3. Maroso, M. et al. Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures. Nat. Med. 16, 413–419 (2010).
4. Devinsky, O. et al. Epilepsy. Nat. Rev. Dis. Primers 4, 18024 (2018).
5. Vezzani, A., Balosso, S. & Ravizza, T. Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy. Nat. Rev. Neurol. 15, 459–472 (2019).
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