Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO)-Reference-Cited by-同舟云学术

Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO)

Published:2022-02-28 Issue:3 Volume:25 Page:317-329
ISSN:1097-6256
Container-title:Nature Neuroscience
language:en
Short-container-title:Nat Neurosci

Author:

Shi Yuan^ORCID,Cui Mochen,Ochs Katharina,Brendel Matthias^ORCID,Strübing Felix L.^ORCID,Briel Nils^ORCID,Eckenweber Florian,Zou Chengyu,Banati Richard B.^ORCID,Liu Guo-Jun^ORCID,Middleton Ryan J.,Rupprecht Rainer,Rudolph Uwe^ORCID,Zeilhofer Hanns Ulrich^ORCID,Rammes Gerhard,Herms Jochen^ORCID,Dorostkar Mario M.^ORCID

Funder

Deutsche Forschungsgemeinschaft

Publisher

Springer Science and Business Media LLC

Subject

General Neuroscience

Link

https://www.nature.com/articles/s41593-022-01013-9.pdf

Reference54 articles.

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2. Rupprecht, R. et al. Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders. Nat. Rev. Drug Discov. 9, 971–988 (2010).

3. Papadopoulos, V. et al. Translocator protein (18 kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function. Trends Pharmacol. Sci. 27, 402–409 (2006).

4. Liu, G.-J. et al. Functional gains in energy and cell metabolism after TSPO gene insertion. Cell Cycle 16, 436–447 (2017).

5. Gut, P., Zweckstetter, M. & Banati, R. B. Lost in translocation: the functions of the 18-kD translocator protein. Trends Endocrinol. Metab. 26, 349–356 (2015).

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