The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition-Reference-Cited by-同舟云学术

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The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition

Published:2008-08-11 Issue:52 Volume:27 Page:6690-6697
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Shiono M,Kobayashi T,Takahashi R,Sun G,Abe M,Zhang D,Wang L,Piao X,Takagi Y,Mineki R,Taka H,Tada N,Sonobe S,Momose S,Ueda M,Hino O

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/onc2008283.pdf

Reference41 articles.

1. Aicher LD, Campbell JS, Yeung RS . (2001). Tuberin phosphorylation regulates its interaction with hamartin. Two proteins involved in tuberous sclerosis. J Biol Chem 276: 21017–21021.

2. Astrinidis A, Henske EP . (2005). Tuberous sclerosis complex: linking growth and energy signaling pathways with human disease. Oncogene 24: 7475–7481.

3. Bissler JJ, McCormack FX, Young LR, Elwing JM, Chuck G, Leonard JM et al. (2008). Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis. N Engl J Med 358: 140–151.

4. Dan HC, Sun M, Yang L, Feldman RI, Sui XM, Ou CC et al. (2002). Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin. J Biol Chem 277: 35364–35370.

5. Dancey JE, Chen HX . (2006). Strategies for optimizing combinations of molecularly targeted anticancer agents. Nat Rev Drug Discov 5: 649–659.

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Establishment of Tsc2-deficient rat embryonic stem cells;International Journal of Oncology;2015-03-03

2. Transgenic expression of the N525S-tuberin variant in Tsc2 mutant (Eker) rats causes dominant embryonic lethality;Scientific Reports;2014-08-04

3. TSC1 Controls Distribution of Actin Fibers through Its Effect on Function of Rho Family of Small GTPases and Regulates Cell Migration and Polarity;PLoS ONE;2013-01-23

4. Pml represses tumour progression through inhibition of mTOR;EMBO Molecular Medicine;2011-03-08

5. Deficiency of the Erc/mesothelin gene ameliorates renal carcinogenesis in Tsc2 knockout mice;Cancer Science;2011-02-09

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