Context-based sensing of orthosomycin antibiotics by the translating ribosome-Reference-Cited by-同舟云学术

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Context-based sensing of orthosomycin antibiotics by the translating ribosome

Published:2022-09-22 Issue:11 Volume:18 Page:1277-1286
ISSN:1552-4450
Container-title:Nature Chemical Biology
language:en
Short-container-title:Nat Chem Biol

Author:

Mangano Kyle,Marks James,Klepacki Dorota,Saha Chayan Kumar,Atkinson Gemma C.,Vázquez-Laslop Nora^ORCID,Mankin Alexander S.^ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences

Foundation for the National Institutes of Health

Knut och Alice Wallenbergs Stiftelse

Kempestiftelserna

Svenska Forskningsrådet Formas

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

https://www.nature.com/articles/s41589-022-01138-9.pdf

Reference60 articles.

1. McCranie, E. K. & Bachmann, B. O. Bioactive oligosaccharide natural products. Nat. Prod. Rep. 31, 1026–1042 (2014).

2. McNicholas, P. M. et al. Evernimicin binds exclusively to the 50S ribosomal subunit and inhibits translation in cell-free systems derived from both Gram-positive and Gram-negative bacteria. Antimicrob. Agents Chemother. 44, 1121–1126 (2000).

3. Lin, J., Zhou, D., Steitz, T. A., Polikanov, Y. S. & Gagnon, M. G. Ribosome-targeting antibiotics: modes of action, mechanisms of resistance, and implications for drug design. Annu. Rev. Biochem. 87, 451–478 (2018).

4. Adrian, P. V. et al. Evernimicin (SCH27899) inhibits a novel ribosome target site: analysis of 23S ribosomal DNA mutants. Antimicrob. Agents Chemother. 44, 3101–3106 (2000).

5. Belova, L., Tenson, T., Xiong, L., McNicholas, P. M. & Mankin, A. S. A novel site of antibiotic action in the ribosome: interaction of evernimicin with the large ribosomal subunit. Proc. Natl Acad. Sci. USA 98, 3726–3731 (2001).

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