Hybrid metagenomic assembly enables high-resolution analysis of resistance determinants and mobile elements in human microbiomes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Link
http://www.nature.com/articles/s41587-019-0191-2.pdf
Reference73 articles.
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2. Liu, L. et al. The human microbiome: a hot spot of microbial horizontal gene transfer. Genomics 100, 265–270 (2012).
3. Penders, J., Stobberingh, E. E., Savelkoul, P. H. M. & Wolffs, P. F. G. The human microbiome as a reservoir of antimicrobial resistance. Front. Microbiol. 4, 87 (2013).
4. Loman, N. J. et al. A culture-independent sequence-based metagenomics approach to the investigation of an outbreak of Shiga-toxigenic Escherichia coli O104:H4. JAMA 309, 1502 (2013).
5. Forbes, J. D., Knox, N. C., Ronholm, J., Pagotto, F. & Reimer, A. Metagenomics: the next culture-independent game changer. Front. Microbiol. 8, 1069 (2017).
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