From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd.2015.21.pdf
Reference174 articles.
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3. Daneman, R., Zhou, L., Kebede, A. A. & Barres, B. A. Pericytes are required for blood–brain barrier integrity during embryogenesis. Nature 468, 562–566 (2010). Demonstrates the role of pericytes in establishing the BBB and shows that barrier function is present even during the fetal period.
4. Abbott, N. J., Ronnback, L. & Hansson, E. Astrocyte–endothelial interactions at the blood–brain barrier. Nat. Rev. Neurosci. 7, 41–53 (2006).
5. Banks, W. A. The blood–brain barrier in neuroimmunology: tales of separation and assimilation. Brain Behav. Immun. 44, 1–8 (2015). Review of mechanisms by which the BBB defines the neuroimmune system.
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