Large-scale integration of the plasma proteome with genetics and disease

Author:

Ferkingstad EgilORCID,Sulem PatrickORCID,Atlason Bjarni A.,Sveinbjornsson Gardar,Magnusson Magnus I.,Styrmisdottir Edda L.,Gunnarsdottir Kristbjorg,Helgason AgnarORCID,Oddsson AsmundurORCID,Halldorsson Bjarni V.ORCID,Jensson Brynjar O.,Zink Florian,Halldorsson Gisli H.ORCID,Masson Gisli,Arnadottir Gudny A.ORCID,Katrinardottir Hildigunnur,Juliusson Kristinn,Magnusson Magnus K.ORCID,Magnusson Olafur Th.,Fridriksdottir Run,Saevarsdottir SaedisORCID,Gudjonsson Sigurjon A.,Stacey Simon N.ORCID,Rognvaldsson SolviORCID,Eiriksdottir ThjodbjorgORCID,Olafsdottir Thorunn A.,Steinthorsdottir ValgerdurORCID,Tragante ViniciusORCID,Ulfarsson Magnus O.ORCID,Stefansson HreinnORCID,Jonsdottir IngileifORCID,Holm HilmaORCID,Rafnar ThorunnORCID,Melsted Pall,Saemundsdottir Jona,Norddahl Gudmundur L.,Lund Sigrun H.ORCID,Gudbjartsson Daniel F.ORCID,Thorsteinsdottir Unnur,Stefansson KariORCID

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Reference57 articles.

1. Buniello, A. et al. The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019. Nucleic Acids Res. 47, D1005–D1012 (2019).

2. Loos, R. J. F. 15 years of genome-wide association studies and no signs of slowing down. Nat. Commun. 11, 5900 (2020).

3. Suhre, K. et al. Connecting genetic risk to disease end points through the human blood plasma proteome. Nat. Commun. 8, 14357 (2017).

4. Sun, B. B. et al. Genomic atlas of the human plasma proteome. Nature 558, 73–79 (2018).

5. Emilsson, V. et al. Co-regulatory networks of human serum proteins link genetics to disease. Science 361, 769–773 (2018).

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