Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression
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Published:2020-01-20
Issue:2
Volume:52
Page:160-166
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ISSN:1061-4036
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Container-title:Nature Genetics
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language:en
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Short-container-title:Nat Genet
Author:
Craig Jamie E., , Han XikunORCID, Qassim AyubORCID, Hassall MarkORCID, Cooke Bailey Jessica N.ORCID, Kinzy Tyler G., Khawaja Anthony P.ORCID, An Jiyuan, Marshall HenryORCID, Gharahkhani PuyaORCID, Igo Robert P.ORCID, Graham Stuart L.ORCID, Healey Paul R., Ong Jue-ShengORCID, Zhou Tiger, Siggs OwenORCID, Law Matthew H.ORCID, Souzeau EmmanuelleORCID, Ridge Bronwyn, Hysi Pirro G.ORCID, Burdon Kathryn P.ORCID, Mills Richard A., Landers John, Ruddle Jonathan B., Agar Ashish, Galanopoulos Anna, White Andrew J. R., Willoughby Colin E.ORCID, Andrew Nicholas H.ORCID, Best Stephen, Vincent Andrea L.ORCID, Goldberg IvanORCID, Radford-Smith GrahamORCID, Martin Nicholas G., Montgomery Grant W.ORCID, Vitart VeroniqueORCID, Hoehn Rene, Wojciechowski Robert, Jonas Jost B.ORCID, Aung Tin, Pasquale Louis R., Cree Angela JaneORCID, Sivaprasad Sobha, Vallabh Neeru A., Viswanathan Ananth C., Pasutto Francesca, Haines Jonathan L., Klaver Caroline C. W.ORCID, van Duijn Cornelia M., Casson Robert J., Foster Paul J.ORCID, Khaw Peng TeeORCID, Hammond Christopher J.ORCID, Mackey David A., Mitchell Paul, Lotery Andrew J.ORCID, Wiggs Janey L.ORCID, Hewitt Alex W.ORCID, MacGregor StuartORCID,
Funder
Department of Health | National Health and Medical Research Council
Publisher
Springer Science and Business Media LLC
Reference51 articles.
1. Weinreb, R. N. & Khaw, P. T. Primary open-angle glaucoma. Lancet 363, 1711–1720 (2004). 2. Tham, Y.-C. et al. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology 121, 2081–2090 (2014). 3. Quigley, H. A. & Broman, A. T. The number of people with glaucoma worldwide in 2010 and 2020. Br. J. Ophthalmol. 90, 262–267 (2006). 4. Chan, M. P. Y. et al. Glaucoma and intraocular pressure in EPIC-Norfolk Eye Study: cross sectional study. BMJ 358, j3889 (2017). 5. Mitchell, P., Smith, W., Attebo, K. & Healey, P. R. Prevalence of open-angle glaucoma in Australia. The Blue Mountains Eye Study. Ophthalmology 103, 1661–1669 (1996).
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