Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids-Reference-Cited by-同舟云学术

Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

Published:2019-03-29 Issue:4 Volume:51 Page:636-648
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Bentley Amy R.^ORCID, ,Sung Yun J.,Brown Michael R.,Winkler Thomas W.,Kraja Aldi T.,Ntalla Ioanna,Schwander Karen,Chasman Daniel I.,Lim Elise,Deng Xuan,Guo Xiuqing,Liu Jingmin,Lu Yingchang,Cheng Ching-Yu,Sim Xueling^ORCID,Vojinovic Dina,Huffman Jennifer E.^ORCID,Musani Solomon K.,Li Changwei,Feitosa Mary F.^ORCID,Richard Melissa A.^ORCID,Noordam Raymond,Baker Jenna,Chen Guanjie,Aschard Hugues,Bartz Traci M.,Ding Jingzhong,Dorajoo Rajkumar^ORCID,Manning Alisa K.^ORCID,Rankinen Tuomo,Smith Albert V.^ORCID,Tajuddin Salman M.^ORCID,Zhao Wei,Graff Mariaelisa,Alver Maris,Boissel Mathilde^ORCID,Chai Jin Fang,Chen Xu^ORCID,Divers Jasmin,Evangelou Evangelos^ORCID,Gao Chuan,Goel Anuj^ORCID,Hagemeijer Yanick^ORCID,Harris Sarah E.,Hartwig Fernando P.^ORCID,He Meian,Horimoto Andrea R. V. R.,Hsu Fang-Chi,Hung Yi-Jen,Jackson Anne U.^ORCID,Kasturiratne Anuradhani,Komulainen Pirjo,Kühnel Brigitte,Leander Karin,Lin Keng-Hung,Luan Jian’an,Lyytikäinen Leo-Pekka^ORCID,Matoba Nana^ORCID,Nolte Ilja M.^ORCID,Pietzner Maik,Prins Bram,Riaz Muhammad,Robino Antonietta,Said M. Abdullah,Schupf Nicole,Scott Robert A.,Sofer Tamar,Stancáková Alena,Takeuchi Fumihiko^ORCID,Tayo Bamidele O.,van der Most Peter J.^ORCID,Varga Tibor V.^ORCID,Wang Tzung-Dau^ORCID,Wang Yajuan,Ware Erin B.^ORCID,Wen Wanqing,Xiang Yong-Bing,Yanek Lisa R.^ORCID,Zhang Weihua,Zhao Jing Hua,Adeyemo Adebowale^ORCID,Afaq Saima,Amin Najaf,Amini Marzyeh,Arking Dan E.,Arzumanyan Zorayr,Aung Tin,Ballantyne Christie,Barr R. Graham,Bielak Lawrence F.,Boerwinkle Eric,Bottinger Erwin P.,Broeckel Ulrich,Brown Morris,Cade Brian E.^ORCID,Campbell Archie^ORCID,Canouil Mickaël^ORCID,Charumathi Sabanayagam^ORCID,Chen Yii-Der Ida,Christensen Kaare^ORCID,Concas Maria Pina^ORCID,Connell John M.,de las Fuentes Lisa^ORCID,de Silva H. Janaka,de Vries Paul S.,Doumatey Ayo,Duan Qing,Eaton Charles B.,Eppinga Ruben N.,Faul Jessica D.,Floyd James S.,Forouhi Nita G.^ORCID,Forrester Terrence,Friedlander Yechiel,Gandin Ilaria,Gao He,Ghanbari Mohsen^ORCID,Gharib Sina A.,Gigante Bruna,Giulianini Franco,Grabe Hans J.,Gu C. Charles,Harris Tamara B.,Heikkinen Sami^ORCID,Heng Chew-Kiat^ORCID,Hirata Makoto^ORCID,Hixson James E.,Ikram M. Arfan^ORCID,Jia Yucheng,Joehanes Roby^ORCID,Johnson Craig,Jonas Jost Bruno^ORCID,Justice Anne E.^ORCID,Katsuya Tomohiro,Khor Chiea Chuen^ORCID,Kilpeläinen Tuomas O.,Koh Woon-Puay,Kolcic Ivana,Kooperberg Charles,Krieger Jose E.^ORCID,Kritchevsky Stephen B.,Kubo Michiaki,Kuusisto Johanna,Lakka Timo A.,Langefeld Carl D.,Langenberg Claudia^ORCID,Launer Lenore J.,Lehne Benjamin,Lewis Cora E.,Li Yize,Liang Jingjing,Lin Shiow,Liu Ching-Ti^ORCID,Liu Jianjun^ORCID,Liu Kiang,Loh Marie,Lohman Kurt K.,Louie Tin,Luzzi Anna,Mägi Reedik,Mahajan Anubha^ORCID,Manichaikul Ani W.,McKenzie Colin A.,Meitinger Thomas,Metspalu Andres,Milaneschi Yuri,Milani Lili^ORCID,Mohlke Karen L.^ORCID,Momozawa Yukihide,Morris Andrew P.^ORCID,Murray Alison D.^ORCID,Nalls Mike A.,Nauck Matthias,Nelson Christopher P.,North Kari E.,O’Connell Jeffrey R.,Palmer Nicholette D.,Papanicolau George J.,Pedersen Nancy L.,Peters Annette,Peyser Patricia A.,Polasek Ozren,Poulter Neil,Raitakari Olli T.,Reiner Alex P.,Renström Frida,Rice Treva K.,Rich Stephen S.,Robinson Jennifer G.,Rose Lynda M.,Rosendaal Frits R.,Rudan Igor^ORCID,Schmidt Carsten O.,Schreiner Pamela J.,Scott William R.,Sever Peter,Shi Yuan,Sidney Stephen,Sims Mario,Smith Jennifer A.^ORCID,Snieder Harold,Starr John M.,Strauch Konstantin,Stringham Heather M.^ORCID,Tan Nicholas Y. Q.,Tang Hua,Taylor Kent D.,Teo Yik Ying,Tham Yih Chung,Tiemeier Henning^ORCID,Turner Stephen T.,Uitterlinden André G.,van Heemst Diana,Waldenberger Melanie,Wang Heming,Wang Lan,Wang Lihua,Wei Wen Bin,Williams Christine A.,Wilson Gregory,Wojczynski Mary K.,Yao Jie,Young Kristin^ORCID,Yu Caizheng,Yuan Jian-Min^ORCID,Zhou Jie,Zonderman Alan B.,Becker Diane M.,Boehnke Michael^ORCID,Bowden Donald W.,Chambers John C.,Cooper Richard S.,de Faire Ulf,Deary Ian J.,Elliott Paul^ORCID,Esko Tõnu^ORCID,Farrall Martin,Franks Paul W.,Freedman Barry I.,Froguel Philippe^ORCID,Gasparini Paolo,Gieger Christian,Horta Bernardo L.^ORCID,Juang Jyh-Ming Jimmy,Kamatani Yoichiro^ORCID,Kammerer Candace M.^ORCID,Kato Norihiro,Kooner Jaspal S.,Laakso Markku^ORCID,Laurie Cathy C.,Lee I-Te,Lehtimäki Terho,Magnusson Patrik K. E.^ORCID,Oldehinkel Albertine J.^ORCID,Penninx Brenda W. J. H.,Pereira Alexandre C.,Rauramaa Rainer,Redline Susan,Samani Nilesh J.,Scott James,Shu Xiao-Ou,van der Harst Pim^ORCID,Wagenknecht Lynne E.,Wang Jun-Sing,Wang Ya Xing^ORCID,Wareham Nicholas J.,Watkins Hugh,Weir David R.,Wickremasinghe Ananda R.,Wu Tangchun,Zeggini Eleftheria,Zheng Wei^ORCID,Bouchard Claude,Evans Michele K.,Gudnason Vilmundur^ORCID,Kardia Sharon L. R.,Liu Yongmei,Psaty Bruce M.,Ridker Paul M.,van Dam Rob M.,Mook-Kanamori Dennis O.,Fornage Myriam,Province Michael A.,Kelly Tanika N.,Fox Ervin R.,Hayward Caroline^ORCID,van Duijn Cornelia M.,Tai E. Shyong,Wong Tien Yin,Loos Ruth J. F.^ORCID,Franceschini Nora,Rotter Jerome I.,Zhu Xiaofeng,Bierut Laura J.,Gauderman W. James,Rice Kenneth^ORCID,Munroe Patricia B.^ORCID,Morrison Alanna C.,Rao Dabeeru C.,Rotimi Charles N.^ORCID,Cupples L. Adrienne^ORCID, , ,

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/s41588-019-0378-y.pdf

Reference68 articles.

1. Willer, C. J. et al. Discovery and refinement of loci associated with lipid levels. Nat. Genet. 45, 1274–1283 (2013).

2. Do, R. et al. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat. Genet. 45, 1345–1352 (2013).

3. Peloso, G. M. et al. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. Am. J. Hum. Genet. 94, 223–232 (2014).

4. Spracklen, C. N. et al. Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. Hum. Mol. Genet. 26, 1770–1784 (2017).

5. Teslovich, T. M. et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466, 707–713 (2010).

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