Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder-Reference-Cited by-同舟云学术

Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder

Published:2024-04-18 Issue:5 Volume:56 Page:792-808
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Nievergelt Caroline M.^ORCID,Maihofer Adam X.,Atkinson Elizabeth G.^ORCID,Chen Chia-Yen^ORCID,Choi Karmel W.^ORCID,Coleman Jonathan R. I.^ORCID,Daskalakis Nikolaos P.^ORCID,Duncan Laramie E.^ORCID,Polimanti Renato^ORCID,Aaronson Cindy,Amstadter Ananda B.,Andersen Soren B.,Andreassen Ole A.^ORCID,Arbisi Paul A.,Ashley-Koch Allison E.^ORCID,Austin S. Bryn,Avdibegoviç Esmina,Babić Dragan,Bacanu Silviu-Alin^ORCID,Baker Dewleen G.^ORCID,Batzler Anthony,Beckham Jean C.,Belangero Sintia^ORCID,Benjet Corina,Bergner Carisa,Bierer Linda M.,Biernacka Joanna M.^ORCID,Bierut Laura J.^ORCID,Bisson Jonathan I.,Boks Marco P.^ORCID,Bolger Elizabeth A.,Brandolino Amber,Breen Gerome,Bressan Rodrigo Affonseca^ORCID,Bryant Richard A.^ORCID,Bustamante Angela C.,Bybjerg-Grauholm Jonas^ORCID,Bækvad-Hansen Marie,Børglum Anders D.^ORCID,Børte Sigrid^ORCID,Cahn Leah,Calabrese Joseph R.,Caldas-de-Almeida Jose Miguel^ORCID,Chatzinakos Chris,Cheema Sheraz,Clouston Sean A. P.^ORCID,Colodro-Conde Lucía^ORCID,Coombes Brandon J.^ORCID,Cruz-Fuentes Carlos S.,Dale Anders M.,Dalvie Shareefa,Davis Lea K.^ORCID,Deckert Jürgen,Delahanty Douglas L.^ORCID,Dennis Michelle F.,Desarnaud Frank,DiPietro Christopher P.,Disner Seth G.^ORCID,Docherty Anna R.,Domschke Katharina^ORCID,Dyb Grete,Kulenović Alma Džubur^ORCID,Edenberg Howard J.^ORCID,Evans Alexandra,Fabbri Chiara,Fani Negar^ORCID,Farrer Lindsay A.^ORCID,Feder Adriana^ORCID,Feeny Norah C.^ORCID,Flory Janine D.,Forbes David,Franz Carol E.^ORCID,Galea Sandro^ORCID,Garrett Melanie E.,Gelaye Bizu^ORCID,Gelernter Joel^ORCID,Geuze Elbert^ORCID,Gillespie Charles F.^ORCID,Goleva Slavina B.,Gordon Scott D.^ORCID,Goçi Aferdita,Grasser Lana Ruvolo^ORCID,Guindalini Camila,Haas Magali,Hagenaars Saskia,Hauser Michael A.,Heath Andrew C.,Hemmings Sian M. J.^ORCID,Hesselbrock Victor,Hickie Ian B.^ORCID,Hogan Kelleigh,Hougaard David Michael^ORCID,Huang Hailiang^ORCID,Huckins Laura M.^ORCID,Hveem Kristian,Jakovljević Miro,Javanbakht Arash,Jenkins Gregory D.^ORCID,Johnson Jessica,Jones Ian^ORCID,Jovanovic Tanja,Karstoft Karen-Inge^ORCID,Kaufman Milissa L.,Kennedy James L.^ORCID,Kessler Ronald C.^ORCID,Khan Alaptagin,Kimbrel Nathan A.,King Anthony P.,Koen Nastassja,Kotov Roman,Kranzler Henry R.,Krebs Kristi^ORCID,Kremen William S.^ORCID,Kuan Pei-Fen,Lawford Bruce R.,Lebois Lauren A. M.^ORCID,Lehto Kelli,Levey Daniel F.^ORCID,Lewis Catrin,Liberzon Israel^ORCID,Linnstaedt Sarah D.^ORCID,Logue Mark W.^ORCID,Lori Adriana,Lu Yi^ORCID,Luft Benjamin J.,Lupton Michelle K.^ORCID,Luykx Jurjen J.^ORCID,Makotkine Iouri,Maples-Keller Jessica L.^ORCID,Marchese Shelby,Marmar Charles,Martin Nicholas G.^ORCID,Martínez-Levy Gabriela A.^ORCID,McAloney Kerrie^ORCID,McFarlane Alexander,McLaughlin Katie A.^ORCID,McLean Samuel A.,Medland Sarah E.^ORCID,Mehta Divya,Meyers Jacquelyn^ORCID,Michopoulos Vasiliki^ORCID,Mikita Elizabeth A.^ORCID,Milani Lili^ORCID,Milberg William,Miller Mark W.^ORCID,Morey Rajendra A.,Morris Charles Phillip^ORCID,Mors Ole,Mortensen Preben Bo,Mufford Mary S.^ORCID,Nelson Elliot C.^ORCID,Nordentoft Merete,Norman Sonya B.^ORCID,Nugent Nicole R.^ORCID,O’Donnell Meaghan^ORCID,Orcutt Holly K.^ORCID,Pan Pedro M.,Panizzon Matthew S.,Pathak Gita A.,Peters Edward S.,Peterson Alan L.^ORCID,Peverill Matthew^ORCID,Pietrzak Robert H.,Polusny Melissa A.^ORCID,Porjesz Bernice,Powers Abigail,Qin Xue-Jun^ORCID,Ratanatharathorn Andrew^ORCID,Risbrough Victoria B.^ORCID,Roberts Andrea L.^ORCID,Rothbaum Alex O.,Rothbaum Barbara O.^ORCID,Roy-Byrne Peter,Ruggiero Kenneth J.,Rung Ariane^ORCID,Runz Heiko^ORCID,Rutten Bart P. F.^ORCID,de Viteri Stacey Saenz,Salum Giovanni Abrahão,Sampson Laura,Sanchez Sixto E.,Santoro Marcos^ORCID,Seah Carina^ORCID,Seedat Soraya^ORCID,Seng Julia S.^ORCID,Shabalin Andrey,Sheerin Christina M.^ORCID,Silove Derrick,Smith Alicia K.^ORCID,Smoller Jordan W.,Sponheim Scott R.^ORCID,Stein Dan J.^ORCID,Stensland Synne,Stevens Jennifer S.^ORCID,Sumner Jennifer A.^ORCID,Teicher Martin H.^ORCID,Thompson Wesley K.,Tiwari Arun K.,Trapido Edward,Uddin Monica,Ursano Robert J.,Valdimarsdóttir Unnur^ORCID,Van Hooff Miranda,Vermetten Eric,Vinkers Christiaan H.^ORCID,Voisey Joanne^ORCID,Wang Yunpeng,Wang Zhewu,Waszczuk Monika,Weber Heike^ORCID,Wendt Frank R.^ORCID,Werge Thomas^ORCID,Williams Michelle A.^ORCID,Williamson Douglas E.,Winsvold Bendik S.^ORCID,Winternitz Sherry^ORCID,Wolf Christiane,Wolf Erika J.^ORCID,Xia Yan,Xiong Ying,Yehuda Rachel^ORCID,Young Keith A.^ORCID,Young Ross McD,Zai Clement C.^ORCID,Zai Gwyneth C.,Zervas Mark,Zhao Hongyu^ORCID,Zoellner Lori A.,Zwart John-Anker^ORCID,deRoon-Cassini Terri,van Rooij Sanne J. H.,van den Heuvel Leigh L., , , , ,Stein Murray B.^ORCID,Ressler Kerry J.^ORCID,Koenen Karestan C.^ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health

Publisher

Springer Science and Business Media LLC

Link

https://www.nature.com/articles/s41588-024-01707-9.pdf

Reference118 articles.

1. Koenen, K. C. et al. Posttraumatic stress disorder in the World Mental Health Surveys. Psychol. Med. 47, 2260–2274 (2017).

2. Davis, L. L. et al. The economic burden of posttraumatic stress disorder in the United States from a societal perspective. J. Clin. Psychiatry 83, 21m14116 (2022).

3. Ferland-Beckham, C. et al. Systematic review and methodological considerations for the use of single prolonged stress and fear extinction retention in rodents. Front. Behav. Neurosci. 15, 652636 (2021).

4. Ressler, K. J. et al. Post-traumatic stress disorder: clinical and translational neuroscience from cells to circuits. Nat. Rev. Neurol. 18, 273–288 (2022).

5. McClellan France, J. & Jovanovic, T. Human fear neurobiology reimagined: can brain-derived biotypes predict fear-based disorders after trauma? Neurosci. Biobehav. Rev. 144, 104988 (2023).

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. cAMP-PKA signaling pathway and anxiety: Where do we go next?;Cellular Signalling;2024-10

2. Novel mechanisms of Anshen Dingzhi prescription against PTSD: Inhibiting DCC to modulate synaptic function and inflammatory responses;Journal of Ethnopharmacology;2024-10

3. Effect of post-traumatic stress disorder on type 2 diabetes and the mediated effect of obesity: a Mendelian randomization study;Frontiers in Endocrinology;2024-09-05

4. What I was thinking/what I would do differently: Biological markers and mechanisms of mental health;Journal of Traumatic Stress;2024-08-28

5. Decoding Sex Differences in PTSD Heritability: A Comprehensive Twin Study;American Journal of Psychiatry;2024-08-01