Structural basis for nucleosome-mediated inhibition of cGAS activity-Reference-Cited by-同舟云学术

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Structural basis for nucleosome-mediated inhibition of cGAS activity

Published:2020-10-13 Issue:12 Volume:30 Page:1088-1097
ISSN:1001-0602
Container-title:Cell Research
language:en
Short-container-title:Cell Res

Author:

Cao Duanfang,Han Xiaonan,Fan Xiaoyi,Xu Rui-Ming,Zhang Xinzheng

Funder

Ministry of Science and Technology of the People’s Republic of China

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology

Link

https://www.nature.com/articles/s41422-020-00422-4.pdf

Reference58 articles.

1. Wu, J. & Chen, Z. J. Innate immune sensing and signaling of cytosolic nucleic acids. Annu. Rev. Immunol. 32, 461–488 (2014).

2. Sun, L., Wu, J., Du, F., Chen, X. & Chen, Z. J. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 339, 786–791 (2013).

3. Li, X. D. et al. Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects. Science 341, 1390–1394 (2013).

4. Wu, J. et al. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science 339, 826–830 (2013).

5. Cai, X., Chiu, Y. H. & Chen, Z. J. The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling. Mol. Cell 54, 289–296 (2014).

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