The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation-Reference-Cited by-同舟云学术

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

Published:2014-06-22 Issue:8 Volume:15 Page:727-737
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Franklin Bernardo S,Bossaller Lukas,De Nardo Dominic,Ratter Jacqueline M,Stutz Andrea,Engels Gudrun,Brenker Christoph,Nordhoff Mark,Mirandola Sandra R,Al-Amoudi Ashraf,Mangan Matthew S,Zimmer Sebastian,Monks Brian G,Fricke Martin,Schmidt Reinhold E,Espevik Terje,Jones Bernadette,Jarnicki Andrew G,Hansbro Philip M,Busto Patricia,Marshak-Rothstein Ann,Hornemann Simone,Aguzzi Adriano,Kastenmüller Wolfgang,Latz Eicke

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/ni.2913.pdf

Reference48 articles.

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2. Latz, E. et al. Activation and regulation of the inflammasomes. Nat. Rev. Immunol. 13, 397–411 (2013).

3. Masumoto, J. et al. ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells. J. Biol. Chem. 274, 33835–33838 (1999).

4. Fernandes-Alnemri, T. et al. The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ. 14, 1590–1604 (2007).

5. Lu, A. et al. Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes. Cell 156, 1193–1206 (2014).

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