Development of pharmacotherapies for drug addiction: a Rosetta Stone approach
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd2828.pdf
Reference209 articles.
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3. Deroche-Gamonet, V., Belin, D. & Piazza, P. V. Evidence for addiction-like behavior in the rat. Science 305, 1014–1017 (2004).
4. Vanderschuren, L. J. & Everitt, B. J. Drug seeking becomes compulsive after prolonged cocaine self-administration. Science 305, 1017–1019 (2004).
5. Heinz, A., Beck, A., Grüsser, S. M., Grace, A. A. & Wrase, J. Identifying the neural circuitry of alcohol craving and relapse vulnerability. Addict. Biol. 14, 108–118 (2009). This study showed a positive correlation between functional brain activation elicited by alcohol-related cues and risk of relapse, suggesting a novel imaging approach in humans.
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