Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer-Reference-Cited by-同舟云学术

Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer

Published:2014-03-31 Issue:11 Volume:34 Page:1341-1353
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Bharadwaj U,Eckols T K,Kolosov M,Kasembeli M M,Adam A,Torres D,Zhang X,Dobrolecki L E,Wei W,Lewis M T,Dave B,Chang J C,Landis M D,Creighton C J,Mancini M A,Tweardy D J

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/onc201472.pdf

Reference61 articles.

1. Zhong Z, Wen Z, Darnell Jr. JE . Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 1994; 264: 95–98.

2. Jing N, Tweardy DJ . Targeting Stat3 in cancer therapy. Anticancer Drugs 2005; 16: 601–607.

3. Johnston PA, Grandis JR . STAT3 signaling: anticancer strategies and challenges. Mol Interv 2011; 11: 18–26.

4. Hanahan D, Weinberg RA . The hallmarks of cancer. Cell 2000; 100: 57–70.

5. Hanahan D, Weinberg RA . Hallmarks of cancer: the next generation. Cell 2011; 144: 646–674.

Cited by 134 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Piperlongumine inhibits hepatocellular carcinoma growth by modulating GSTP1 and restraining the STAT3 signaling pathway;Journal of Functional Foods;2024-07

2. Inhibition of the thioredoxin system for radiosensitization therapy of cancer;European Journal of Medicinal Chemistry;2024-03

3. Bruceantinol targeting STAT3 exerts promising antitumor effects in in vitro and in vivo osteosarcoma models;Molecular Carcinogenesis;2024-03

4. Piperlongumine inhibits antioxidant enzymes, increases ROS levels, induces DNA damage and G2/M cell cycle arrest in breast cell lines;Journal of Toxicology and Environmental Health, Part A;2024-01-27

5. Piperlongumine based nanomedicine impairs glycolytic metabolism in triple negative breast cancer stem cells through modulation of GAPDH & FBP1;Phytomedicine;2024-01