Mesenchymal stem cells overexpressing BMP-9 by CRISPR-Cas9 present high in vitro osteogenic potential and enhance in vivo bone formation-Reference-Cited by-同舟云学术

Mesenchymal stem cells overexpressing BMP-9 by CRISPR-Cas9 present high in vitro osteogenic potential and enhance in vivo bone formation

Published:2021-03-08 Issue:12 Volume:28 Page:748-759
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Freitas Gileade P.^ORCID,Lopes Helena B.,Souza Alann T. P.,Gomes Maria Paula O.^ORCID,Quiles Georgia K.,Gordon Jonathan,Tye Coralee^ORCID,Stein Janet L.^ORCID,Stein Gary S.,Lian Jane B.,Beloti Marcio M.,Rosa Adalberto L.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

https://www.nature.com/articles/s41434-021-00248-8.pdf

Reference58 articles.

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2. Walmsley GG, Ransom RC, Zielins ER, Leavitt T, Flacco JS, Hu MS, et al. Stem cells in bone regeneration. Stem Cell Rev Rep. 2016;12:524–9. https://doi.org/10.1007/s12015-016-9665-5

3. Souza ATP, Freitas GP, Lopes HB, Ferraz EP, Oliveira FS, Beloti MM, et al. Effect of cell therapy with allogeneic osteoblasts on bone repair of rat calvaria defects. Cytotherapy. 2018;20:1267–77. https://doi.org/10.1016/j.jcyt.2018.06.010

4. Freitas GP, Lopes HB, Souza ATP, Oliveira PGFP, Almeida ALG, Souza LEB, et al. Cell therapy: effect of locally injected mesenchymal stromal cells derived from bone marrow or adipose tissue on bone regeneration of rat calvarial defects. Sci Rep. 2019;9:13476 https://doi.org/10.1038/s41598-019-50067-6

5. Freitas GP, Lopes HB, Souza ATP, Oliveira PGFP, Almeida ALG, Coelho PG, et al. Effect of cell therapy with osteoblasts differentiated from bone marrow or adipose tissue stromal cells on bone repair. Regen Med. 2019;14:1107–19. https://doi.org/10.2217/rme-2019-0036

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