Central and peripheral GLP-1 systems independently suppress eating-Reference-Cited by-同舟云学术

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Central and peripheral GLP-1 systems independently suppress eating

Published:2021-02 Issue:2 Volume:3 Page:258-273
ISSN:2522-5812
Container-title:Nature Metabolism
language:en
Short-container-title:Nat Metab

Author:

Brierley Daniel I.^ORCID,Holt Marie K.,Singh Arashdeep^ORCID,de Araujo Alan^ORCID,McDougle Molly,Vergara Macarena^ORCID,Afaghani Majd H.^ORCID,Lee Shin Jae,Scott Karen^ORCID,Maske Calyn,Langhans Wolfgang^ORCID,Krause Eric^ORCID,de Kloet Annette,Gribble Fiona M.^ORCID,Reimann Frank^ORCID,Rinaman Linda^ORCID,de Lartigue Guillaume^ORCID,Trapp Stefan^ORCID

Funder

Wellcome Trust

RCUK | Medical Research Council

U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Physiology (medical),Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://www.nature.com/articles/s42255-021-00344-4.pdf

Reference67 articles.

1. Knudsen, L. B. & Lau, J. The discovery and development of liraglutide and semaglutide. Front. Endocrinol. 10, 155 (2019).

2. Turton, M. D. et al. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 379, 69–72 (1996).

3. Trapp, S. & Richards, J. E. The gut hormone glucagon-like peptide-1 produced in brain: is this physiologically relevant? Curr. Opin. Pharmacol. 13, 964–969 (2013).

4. Müller, T. D. et al. Glucagon-like peptide 1 (GLP-1). Mol. Metab. 30, 72–130 (2019).

5. Gaykema, R. P. et al. Activation of murine pre-proglucagon–producing neurons reduces food intake and body weight. J. Clin. Invest. 127, 1031–1045 (2017).

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