The pleiotropic structure of the genotype–phenotype map: the evolvability of complex organisms
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Molecular Biology
Link
http://www.nature.com/articles/nrg2949.pdf
Reference68 articles.
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3. Wolf, J. B., Pomp, D., Eisen, E. J., Cheverud, J. M. & Leamy, L. J. The contribution of epistatic pleiotropy to the genetic architecture of covariation among polygenic traits in mice. Evol. Dev. 8, 468–476 (2006).
4. Tyler, A. L., Asselbergs, F. W., Williams, S. M. & Moore, J. H. Shadows of complexity: what biological networks reveal about epistasis and pleiotropy. Bioessays 31, 220–227 (2009).
5. Plomin, R., Haworth, C. M. & Davis, O. S. Common disorders are quantitative traits. Nature Reviews Genetics 10, 872–878 (2009).
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