Metformin facilitates anti-PD-L1 efficacy through the regulation of intestinal microbiota
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Immunology
Link
https://www.nature.com/articles/s41435-023-00234-7.pdf
Reference36 articles.
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3. Elgendy M, Ciro M, Hosseini A, Weiszmann J, Mazzarella L, Ferrari E, et al. Combination of Hypoglycemia and Metformin impairs tumor metabolic plasticity and growth by modulating the PP2A-GSK3beta-MCL-1 axis. Cancer Cell. 2019;35:798–815.e5.
4. Cha JH, Yang WH, Xia W, Wei Y, Chan LC, Lim SO, et al. Metformin promotes antitumor immunity via endoplasmic-reticulum-associated degradation of PD-L1. Mol Cell. 2018;71:606–20.e7.
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