Interleukin-3 gets a fresh start in the brain
Author:
Funder
U.S. Department of Health & Human Services | National Institutes of Health
Cure Alzheimer’s Fund
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics,Immunology
Link
https://www.nature.com/articles/s41435-023-00231-w.pdf
Reference13 articles.
1. Attfield KE, Jensen LT, Kaufmann M, Friese MA, Fugger L. The immunology of multiple sclerosis. Nat Rev Immunol. 2022;22:734–50.
2. Leng F, Edison P. Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here? Nat Rev Neurol. 2021;17:157–72.
3. McAlpine CS, Park J, Griciuc A, Kim E, Choi SH, Iwamoto Y, et al. Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease. Nature. 2021;595:701–6.
4. Kiss MG, Mindur JE, Yates AG, Lee D, Fullard JF, Anzai A, et al. Interleukin-3 coordinates glial–peripheral immune crosstalk to incite multiple sclerosis. Immunity. 2023;56:1502–14.
5. Pluznik DH, Sachs L. The cloning of normal ‘mast’ cells in tissue culture. J Cell Physiol. 1965;66:319–24.
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