Tracking membrane and secretory immunoglobulin α heavy chain mRNA variation during B‐cell differentiation by real‐time quantitative polymerase chain reaction
Author:
Affiliation:
1. The Institute for Immunology and Allergy Research, Westmead Hospital Westmead New South Wales Australia
2. Department of Immunopathology, Westmead Hospital Westmead New South Wales Australia
Publisher
Wiley
Subject
Cell Biology,Immunology,Immunology and Allergy
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1440-1711.2001.01033.x
Reference33 articles.
1. Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways
2. Changes in J chain and mu chain RNA expression as a function of B cell differentiation.
3. Developmental Regulation of Secreted and Membrane Forms of Immunoglobulin μ Chain
4. Relative position and strengths of poly(A) sites as well as transcription termination are critical to membrane versus secreted mu-chain expression during B-cell development.
5. Sequences near the 3' secretion-specific polyadenylation site influence levels of secretion-specific and membrane-specific IgG2b mRNA in myeloma cells.
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