Population pharmacokinetics of thioTEPA and its active metabolite TEPA in patients undergoing high-dose chemotherapy

Author:

Huitema Alwin D. R.,Mathôt Ron A. A.,Tibben Matthijs M.,Schellens Jan H. M.,Rodenhuis Sjoerd,Beijnen Jos H.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference40 articles.

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2. High-dose chemotherapy for solid tumors;Van Der Wall;Cancer Treat Rev,1995

3. Correlation between plasma pharmacokinetics and in vitro cytotoxicity of thiotepa (tt) and tepa (tp);Cole;Proc Am Ass Clin Oncol,1989

4. Thiono compounds. 4. in vitro mutagenic and antineoplastic activity of tepa and thio-tepa;Breau;Cell Biol Toxicol,1984

5. Evidence for enzymatic activation and oxygen involvement in cytotoxicity and antitumor activity of N,N',N′′-triethylenethiophosphoramide;Teicher;Cancer Res,1989

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