Low antigen dose favours selection of somatic mutants with hallmarks of antibody affinity maturation
Author:
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1046/j.1365-2567.1998.00423.x/fullpdf
Reference22 articles.
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3. Somatic mutation and the maturation of immune response to 2-phenyloxazolone.;Griffiths;Nature,1984
4. Mutation drift and repertoire shift in the maturation of the immune response.;Berek;Immunol Rev,1987
5. Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes;Betz;Immunol. Today,1993
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