Simultaneous Assessment of Hepatic Transport and Metabolism Pathways with a Single Probe Using Individualized PBPK Modeling of 14CO2 Production Rate Data
Author:
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Subject
Pharmacology,Molecular Medicine
Reference48 articles.
1. Muscle Distribution of Antimicrobial Agents after a Single Intravenous Administration to Rats
2. Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver
3. The Drug Transporter−Metabolism Alliance: Uncovering and Defining the Interplay
4. Prediction of the volume of distribution of a drug: which tissue-plasma partition coefficients are needed?
5. Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver
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1. Using Individualized Patient Data for Prediction of Population Dosing Recommendations Versus Predictions of Individualized Patient Dosing;The Journal of Clinical Pharmacology;2021-04-12
2. Application of Individualized PBPK Modeling of Rate Data to Evaluate the Effect of Hemodialysis on Nonrenal Clearance Pathways;The Journal of Clinical Pharmacology;2021-02-16
3. Dose Optimization in Kidney Disease: Opportunities for PBPK Modeling and Simulation;The Journal of Clinical Pharmacology;2020-11
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