Small Molecule Allosteric Modulation of the Glucagon-Like Peptide-1 Receptor Enhances the Insulinotropic Effect of Oxyntomodulin-Reference-Cited by-同舟云学术

Small Molecule Allosteric Modulation of the Glucagon-Like Peptide-1 Receptor Enhances the Insulinotropic Effect of Oxyntomodulin

Published:2012-08-28 Issue:6 Volume:82 Page:1066-1073
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Willard Francis S.,Wootten Denise,Showalter Aaron D.,Savage Emilia E.,Ficorilli James,Farb Thomas B.,Bokvist Krister,Alsina-Fernandez Jorge,Furness Sebastian G. B.,Christopoulos Arthur,Sexton Patrick M.,Sloop Kyle W.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference42 articles.

1. Allosteric Modulators of the Adenosine A1 Receptor: Synthesis and Pharmacological Evaluation of 4-Substituted 2-Amino-3-benzoylthiophenes

2. The Impact of Orthosteric Radioligand Depletion on the Quantification of Allosteric Modulator Interactions

3. Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure

4. Oxyntomodulin (glicentin-(33–69)): pharmacokinetics, binding to liver cell membranes, effects on isolated perfused pig pancreas, and secretion from isolated perfused lower small intestine of pigs

5. Translational efficiency of EMCV IRES in bicistronic vectors is dependent upon IRES sequence and gene location

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