Low Molecular Weight Acids and Organic Anion Transporting Polypeptide (OATP1B)-Mediated Hepatic Clearance: In Vitro and In Vivo Evaluation Using Novel Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (Dustats)-Reference-Cited by-同舟云学术

Low Molecular Weight Acids and Organic Anion Transporting Polypeptide (OATP1B)-Mediated Hepatic Clearance: In Vitro and In Vivo Evaluation Using Novel Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (Dustats)

Published:2024-02-22 Issue:5 Volume:52 Page:399-407
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Bi Yi-An,Jordan Samantha,King-Ahmad Amanda,West Mark A.,Yamaguchi Emi,Ryu Sangwoo,Mathialagan Sumathy,Tess David A.,Varma Manthena V.S.^ORCID

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Reference24 articles.

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3. Quantitative Contribution of Six Major Transporters to the Hepatic Uptake of Drugs: “SLC-Phenotyping” Using Primary Human Hepatocytes

4. Bi YA Jordan S King-Ahmad A West M Varma MVS (2024) Mechanistic determinants of daprodustat drug-drug interactions and pharmacokinetics in hepatic dysfunction and chronic kidney disease: significance of transporter-enzyme interplay. Clin Pharmacol Ther DOI: 10.1002/cpt.3215 [published ahead of print].

5. Reliable Rate Measurements for Active and Passive Hepatic Uptake Using Plated Human Hepatocytes

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1. Mechanistic Account of Distinct Change in Organic Anion Transporting Polypeptide 1B (OATP1B) Substrate Pharmacokinetics during OATP1B-Mediated Drug-Drug Interactions Using Physiologically Based Pharmacokinetic Modeling;Drug Metabolism and Disposition;2024-05-13