Chronic Ca2+/Calmodulin-Dependent Protein Kinase II Inhibition Rescues Advanced Heart Failure

Author:

Liu Yixi,Shao Qun,Cheng Heng-Jie,Li Tiankai,Zhang Xiaowei,Callahan Michael F.,Herrington David,Kitzman Dalane,Zhao David,Cheng Che-Ping

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference60 articles.

1. CaMKII and a failing strategy for growth in heart

2. Oxidant stress promotes disease by activating CaMKII

3. KN-93, an inhibitor of multifunctional Ca++/calmodulin-dependent protein kinase, decreases early afterdepolarizations in rabbit heart;Anderson;J Pharmacol Exp Ther,1998

4. The   isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload

5. Reversion of cardiac dysfunction by a novel orally available calcium/calmodulin-dependent protein kinase II inhibitor, RA306, in a genetic model of dilated cardiomyopathy;Beauverger;Cardiovasc Res,2020

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