Preclinical Efficacy and Safety of the Novel Antidiabetic, Antiobesity MetAP2 Inhibitor ZGN-1061-Reference-Cited by-同舟云学术

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Preclinical Efficacy and Safety of the Novel Antidiabetic, Antiobesity MetAP2 Inhibitor ZGN-1061

Published:2018-02-28 Issue:2 Volume:365 Page:301-313
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Burkey Bryan F.,Hoglen Niel C.,Inskeep Philip,Wyman Margaret,Hughes Thomas E.,Vath James E.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference20 articles.

1. Angiogenesis Inhibitor, TNP-470, Prevents Diet-Induced and Genetic Obesity in Mice

2. Treatment of Cells with the Angiogenic Inhibitor Fumagillin Results in Increased Stability of Eukaryotic Initiation Factor 2-Associated Glycoprotein, p67, and Reduced Phosphorylation of Extracellular Signal-Regulated Kinases

3. Robust reductions of excess weight and hyperphagia by beloranib in rat models of genetic and hypothalamic obesity;Elfers;Endocrinology,2017

4. Regulation of G1 Cell Cycle Progression: Distinguishing the Restriction Point from a Nutrient-Sensing Cell Growth Checkpoint(s)

5. Mechanistic Investigation of Imatinib-Induced Cardiac Toxicity and the Involvement of c-Abl Kinase

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1. Methionine aminopeptidases: Potential therapeutic target for microsporidia and other microbes;Journal of Eukaryotic Microbiology;2024-07-22

2. Perspectives on the drug discovery of intestinal protozoan parasites;Intestinal Parasites - New Developments in Diagnosis, Treatment, Prevention and Future Directions [Working Title];2024-06-04

3. Methionine aminopeptidases;Metalloenzymes;2024

4. Updates on Obesity in Prader-Willi Syndrome: From Genetics to Management;The Ewha Medical Journal;2023-12-31

5. Fumagillin inhibits growth of the enteric protozoan parasite Entamoeba histolytica by covalently binding to and selectively inhibiting methionine aminopeptidase 2;Antimicrobial Agents and Chemotherapy;2023-11-15

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