The CYP2D6 Humanized Mouse: Effect of the HumanCYP2D6 Transgene and HNF4α on the Disposition of Debrisoquine in the Mouse-Reference-Cited by-同舟云学术

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The CYP2D6 Humanized Mouse: Effect of the HumanCYP2D6 Transgene and HNF4α on the Disposition of Debrisoquine in the Mouse

Published:2001-12-01 Issue:6 Volume:60 Page:1260-1267
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Corchero Javier,Granvil Camille P.,Akiyama Taro E.,Hayhurst Graham P.,Pimprale Satish,Feigenbaum Lionel,Idle Jeffrey R.,Gonzalez Frank J.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference36 articles.

1. Animal modelling of human polymorphic drug oxidation: the metabolism of debrisoquine and phenacetin in rat inbred strains.;Al-Dabbagh;J Pharm Pharmacol,1981

2. Metabolism of debrisoquine sulphate in rat, dog and man.;Allen;Xenobiotica,1976

3. Bile acids, oxidative stress, and renal function in biliary obstruction.;Bomzon;Semin Nephrol,1997

4. First-pass metabolism of imipramine and desipramine: impact of the sparteine oxidation phenotype.;Brøsen;Clin Pharmacol Ther,1988

5. Recent developments in hepatic drug oxidation. Implications for clinical pharmacokinetics.;Brøsen;Clin Pharmacokinet,1990

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