Epigenetic Mechanisms Contribute to Intraindividual Variations of Drug Metabolism Mediated by Cytochrome P450 Enzymes

Author:

Jin JingORCID,Zhong Xiao-boORCID

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference158 articles.

1. Latent overexpression of hepatic CYP2C7 in adult male and female rats neonatally exposed to phenobarbital: a developmental profile of gender-dependent P450s;Agrawal;J Pharmacol Exp Ther,2000

2. Phenobarbital induction of hepatic CYP2B1 and CYP2B2: pretranscriptional and post-transcriptional effects of gender, adult age, and phenobarbital dose;Agrawal;Mol Pharmacol,1996

3. Phenobarbital-Imprinted Overinduction of Adult Constituent CYP Isoforms

4. Genetic Polymorphism of CYP1A2 in Ethiopians Affecting Induction and Expression: Characterization of Novel Haplotypes with Single-Nucleotide Polymorphisms in Intron 1

5. Evaluation of the Assumptions of an Ontogeny Model of Rat Hepatic Cytochrome P450 Activity

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