P-Glycoprotein Limits Oral Availability, Brain, and Fetal Penetration of Saquinavir Even with High Doses of Ritonavir-Reference-Cited by-同舟云学术

P-Glycoprotein Limits Oral Availability, Brain, and Fetal Penetration of Saquinavir Even with High Doses of Ritonavir

Published:2001-04-01 Issue:4 Volume:59 Page:806-813
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Huisman Maarten T.,Smit Johan W.,Wiltshire Hugh R.,Hoetelmans Richard M. W.,Beijnen Jos. H.,Schinkel Alfred H.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

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2. Ritonavir and saquinavir combination therapy for the treatment of HIV infection

3. Placental transfer of ritonavir with zidovudine in the ex vivo placental perfusion model

4. Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes.;Choo;Drug Metab Dispos,2000

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