Biochemical Markers in Covid-19 Patients in Tripoli, Libya; A Retrospective Study

Abstract

Covid 19 can cause fatal pneumonia and serious complications. In the course of the disease the levels of different biochemical parameters increased and these parameters provide important information about the prognosis of the disease. The aim of this study was to investigate these biomarkers and to evaluate the relationship between biochemical parameters and length of stay in Covid 19 patients. A retrospective study was conducted from October 2020 to December 2021. A total of 156 Covid 19 patients hospitalized in Meitiga Military hospital were included. The demographic characteristics, length of stay, and biochemical parameters of the patients were scanned from the hospital's database and patient files and recorded. Patients were grouped according to the length of stay; 1st group: after 3 to 5 days, 2nd group: from 8 to 12 days, and 3rd group: after 13 days and more. Most of admitted cases were males, the majority of the participants were in age above 65 years old. CRP, FER, LDH, and D-dimer were gradually increased to the maximum mean; 131.4±67, 1052.3±710.1, 586±128.9, and 1196.2±409.1, respectively after 8 to 12 days and return to normal range after 13 days. To conclude, there is a positive correlation between the levels of these biomarkers and the prolongation of hospitalization in COVID-19 patients and these parameters can be associated with the severity disease.