Slow but Steady Wins the Race: Dissimilarities among New Dual Inhibitors of the Wild-Type and the V27A Mutant M2 Channels of Influenza A Virus-Reference-Cited by-同舟云学术

Slow but Steady Wins the Race: Dissimilarities among New Dual Inhibitors of the Wild-Type and the V27A Mutant M2 Channels of Influenza A Virus

Published:2017-04-24 Issue:9 Volume:60 Page:3727-3738
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Barniol-Xicota Marta¹,Gazzarrini Sabrina²,Torres Eva¹,Hu Yanmei³⁴,Wang Jun³⁴^ORCID,Naesens Lieve⁵,Moroni Anna²,Vázquez Santiago¹^ORCID

Affiliation:

1. Laboratori de Química Farmacèutica (Unitat Associada al CSIC), Facultat de Farmàcia i Ciències de l’Alimentació, and Institute of Biomedicine (IBUB), Universitat de Barcelona, Av. Joan XXIII, 27-31, Barcelona E-08028, Spain

2. Department of Biosciences and National Research Council (CNR) Biophysics Institute (IBF), University of Milan, Via Celoria 26, 20133 Milan, Italy

3. Department of Pharmacology and Toxicology, College of Pharmacy, The University of Arizona, Tucson, Arizona 85721, United States

4. BI05 Institute, The University of Arizona, Tucson, Arizona 85721, United States

5. Rega Institute for Medical Research, KU Leuven, B-3000 Leuven, Belgium

Funder

Ministerio de Ciencia e Innovación

National Institute of Allergy and Infectious Diseases

Foundation for the National Institutes of Health

Geconcerteerde Onderzoeksacties

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01758

Reference67 articles.

1. Emerging Antiviral Strategies to Interfere with Influenza Virus Entry

2. The M2 Proton Channels of Influenza A and B Viruses

3. Structural and dynamic mechanisms for the function and inhibition of the M2 proton channel from influenza A virus

4. Structural basis for proton conduction and inhibition by the influenza M2 protein

5. Activation and Proton Transport Mechanism in Influenza A M2 Channel

Cited by 20 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Tackling Influenza A virus by M2 ion channel blockers: Latest progress and limitations;European Journal of Medicinal Chemistry;2024-03

2. Targeting Protein–Protein Interfaces with Peptides: The Contribution of Chemical Combinatorial Peptide Library Approaches;International Journal of Molecular Sciences;2023-04-25

3. Amantadine variant – aryl conjugates that inhibit multiple M2 mutant – amantadine resistant influenza a viruses;European Journal of Medicinal Chemistry Reports;2022-12

4. Amantadine Variant – Aryl Conjugates that Inhibit Multiple M2 Mutant – Amantadine Resistant Influenza A Viruses;SSRN Electronic Journal;2022

5. Practical and Regioselective Synthesis of C-4-Alkylated Pyridines;Journal of the American Chemical Society;2021-07-28