New Insights into Human 17β-Hydroxysteroid Dehydrogenase Type 14: First Crystal Structures in Complex with a Steroidal Ligand and with a Potent Nonsteroidal Inhibitor-Reference-Cited by-同舟云学术

New Insights into Human 17β-Hydroxysteroid Dehydrogenase Type 14: First Crystal Structures in Complex with a Steroidal Ligand and with a Potent Nonsteroidal Inhibitor

Published:2016-07-12 Issue:14 Volume:59 Page:6961-6967
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bertoletti Nicole¹,Braun Florian¹,Lepage Mahalia¹,Möller Gabriele²,Adamski Jerzy²³⁴,Heine Andreas¹,Klebe Gerhard¹,Marchais-Oberwinkler Sandrine¹

Affiliation:

1. Institute for Pharmaceutical Chemistry, Philipps University Marburg, 35037 Marburg, Germany

2. German Research Center for Environmental Health, Institute of Experimental Genetics, Genome Analysis Center, Helmholtz Zentrum München, 85764 Neuherberg, Germany

3. Lehrstuhl für Experimentelle Genetik, Technische Universität München, 85350 Freising-Weihenstephan, Germany

4. German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany

Funder

Deutscher Akademischer Austauschdienst

Deutsche Forschungsgemeinschaft

European Commission

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00293