Design, Synthesis, and Evaluation of 11C-Labeled 3-Acetyl-Indole Derivatives as a Novel Positron Emission Tomography Imaging Agent for Diacylglycerol Kinase Gamma (DGKγ) in Brain-Reference-Cited by-同舟云学术

Design, Synthesis, and Evaluation of 11C-Labeled 3-Acetyl-Indole Derivatives as a Novel Positron Emission Tomography Imaging Agent for Diacylglycerol Kinase Gamma (DGKγ) in Brain

Published:2021-08-04 Issue:16 Volume:64 Page:11990-12002
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hattori Yasushi¹^ORCID,Yamasaki Tomoteru²,Ohashi Tomohiro¹,Miyanohana Yuhei¹,Kusumoto Tomokazu¹,Maeda Ryouta¹,Miyamoto Maki¹,Debori Yasuyuki¹,Hata Akito¹,Zhang Yiding²,Wakizaka Hidekatsu²,Wakabayashi Takeshi¹,Fujinaga Masayuki²,Yamashita Ryo¹,Zhang Ming-Rong²,Koike Tatsuki¹^ORCID

Affiliation:

1. Takeda Pharmaceutical Company Limited, 26-1 Muraoka-Higashi, 2-Chome, Fujisawa, Kanagawa 251-8555, Japan

2. Department of Advanced Nuclear Medicine Sciences, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1, Anagawa, Inage-ku, Chiba 263-8555, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00584

Reference45 articles.

1. Mammalian Diacylglycerol Kinases, a Family of Lipid Kinases with Signaling Functions

2. Properties and functions of diacylglycerol kinases

3. Diacylglycerol kinases: Why so many of them?

4. Diacylglycerol kinases: at the hub of cell signalling

5. Regulation and Functions of Diacylglycerol Kinases

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