Discovery of Novel cccDNA Reducers toward the Cure of Hepatitis B Virus Infection-Reference-Cited by-同舟云学术

Discovery of Novel cccDNA Reducers toward the Cure of Hepatitis B Virus Infection

Published:2022-08-16 Issue:16 Volume:65 Page:10938-10955
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chen Dongdong¹^ORCID,Tan Xuefei¹^ORCID,Chen Wenming¹,Liu Yongfu¹,Li Chao¹,Wu Jun¹,Zheng Jiamin¹,Shen Hong C.¹^ORCID,Zhang Meifang²,Wu Waikwong²,Wang Lin³,Xiong Jing³,Dai Jieyu⁴,Sun Kai⁴,Zhang Jitao David⁵,Xiang Kunlun⁶,Li Baocun⁶,Ni XiaoJu⁶,Zhu Qihui⁶,Gao Lu⁶,Wang Li⁶,Feng Song¹

Affiliation:

1. Department of Medicinal Chemistry, Roche Innovation Center Shanghai, Roche Pharma Research & Early Development, Building 5, No. 371, Lishizhen Road, Shanghai 201203, China

2. Lead Discovery, Roche Innovation Center Shanghai, Roche Pharma Research & Early Development, Building 5, No. 371, Lishizhen Road, Shanghai 201203, China

3. pCMC, Roche Innovation Center Shanghai, Roche Pharma Research & Early Development, Building 5, No. 371, Lishizhen Road, Shanghai 201203, China

4. Pharmaceutical Sciences, Roche Innovation Center Shanghai, Roche Pharma Research & Early Development, Building 5, No. 371, Lishizhen Road, Shanghai 201203, China

5. Pharmaceutical Science, Roche Innovation Center Basel, Roche Pharma Research & Early Development, Grenzacherstrasse 124, Basel CH-4070, Switzerland

6. Discovery Virology, Roche Innovation Center Shanghai, Roche Pharma Research & Early Development, Building 5, No. 371, Lishizhen Road, Shanghai 201203, China

Funder

F. Hoffmann-La Roche

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c02215

Reference41 articles.

1. WHO. Hepatitis B: world health organization fact sheet 204. http://www.who.int/mediacentre/factsheets/fs204/en/ (Date of access Dec 18, 2020).

2. WHO. Global Hepatitis Report; WHO: Geneva, Switzerland, 2017.

3. Requirements for global elimination of hepatitis B: a modelling study

4. Recent Advances in Understanding, Diagnosing, and Treating Hepatitis B Virus Infection

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